The Help Live Tiffany Arias Foundation

URGENT!!! The family of ten month old Tiffany Arias Martinez, from the Dominican Republic, Is in urgent need of help to save their daughters life. They are trying to raise money to pay for a liver transplant.

Wendy Martinez explains that her daughter’s biliary are obstructed and that’s the reason why she needs a transplant liver before she turns one. She has a donor in Argentina, but her family lacks the resources necessary to pay the transplant which cost about US$90 thousands.

If you have any information about some way we can raise money, get help form a big company, foundation call 201-640-9774
Those interested in given a donation to help tiffany live you can call 829-851-2416 or 829-908-4929. For donations

PLEASE YOUR CONTRIBUTION CAN HELP TIFFANY LIVE.

Biliary atresia

Biliary atresia is a rare condition in newborn infants in which the common bile duct between the liver and the small intestine is blocked or absent. If unrecognized, the condition leads to liver failure — but not kernicterus, as the liver is still able to conjugate bilirubin, and conjugated bilirubin is unable to cross the blood-brain barrier. The cause of the condition is unknown. The only effective treatments are certain surgeries such as the kasai procedure, or liver transplantation.

Pathophysiology

There is no known cause of biliary atresia. There have been many theories about ethiopathogenesis such as Reovirus 3 infection, congenital malformation, congenital CMV infection, autoimmune theory. This means that the etiology and pathogenesis of biliary atresia are largely unknown. However, there have been extensive studies about the pathogenesis and proper management of progressive liver fibrosis, which is arguably one of the most important aspects of biliary atresia patients. As the biliary tract cannot transport bile to the intestine, bile is retained in the liver (known as stasis) and results in cirrhosis of the liver. Proliferation of the small bile ductules occur, and peribiliary fibroblasts become activated. These “reactive” biliary epithelial cells in cholestasis, unlike normal condition, produce and secrete various cytokines such as CCL-2 or MCP-1, Tumor necrosis factor (TNF), Interleukin-6 (IL-6), TGF-beta, Endothelin (ET), and nitric oxide (NO). Among these, TGF-beta is the most important profibrogenic cytokine that can be seen in liver fibrosis in chronic cholestasis. During the chronic activation of biliary epithelium and progressive fibrosis, afflicted patients eventually show signs and symptoms of portal hypertension (esophagogastric varix bleeding, hypersplenism, hepatorenal syndrome(HRS), hepatopulmonary syndrome(HPS)). The latter two syndromes are essentially caused by systemic mediators that maintain the body within the hyperdynamic states. There are three main types of extrahepatic biliary atresia:- Type I: atresia restricted to the common bile duct. Type II: atresia of the common hepatic duct. Type III: atresia of the right and left hepatic duct. Associated anomalies include, in about 20% cases, cardiac lesions, polysplenia, situs inversus, absent vena cava and a preduodenal portal vein.

Local news has tried to inform the nation but its not enough

Documents of tiffany arias medical diagnostic and news

Thank god for human like you, that have a heart and contribute to a good cause

MAKE YOUR DONATIONS HERE.
HELP LINE TIFFANY ARIAS FOUNDATION
ACCOUNT: 8046810443
BANK: PNC
OR

BANK ACCOUNT FROM DOMINICAN REPUBLIC
ACCOUNT#240-159376-5 RD/200-02-242-000767-8US THE BANK OF ” banco de reservas
MAKE IT OUT TO: Wendy Martinez (Tiffany ‘s mother)
or